منابع مشابه
Perchloroethylene White Paper - Novermber 2008
Perchloroethylene, also known as tetrachloroethylene or perc, has been used safely in industry for over 50 years. It is an effective, nonfl ammable solvent that does not contribute to the formation of smog (ground-level ozone) or to the depletion of stratospheric ozone. The US Environmental Protection Agency (EPA) has approved the use of perchloroethylene as a replacement for stratospheric ozon...
متن کاملHepatic and renal toxicities associated with perchloroethylene.
Metabolism of perchloroethylene (Perc) occurs by cytochrome P450-dependent oxidation and glutathione (GSH) conjugation. The cytochrome P450 pathway generates tri- and dichloroacetate as metabolites of Perc, and these are associated with hepatic toxicity and carcinogenicity. The GSH conjugation pathway is associated with generation of reactive metabolites selectively in the kidneys and with Perc...
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ژورنال
عنوان ژورنال: BMJ
سال: 1971
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.3.5766.115-b